Born on March 27, 1964, in Pančevo, Slobodan Beštić graduated from the Faculty of Dramatic Arts in Belgrade in 1987, under the mentorship of Prof. Predrag Bajčetić. He began his professional career at the Yugoslav Drama Theatre (1987–2001) and later joined the National Theatre in Belgrade.
Throughout his career, he has delivered acclaimed performances in a wide range of theatrical works, including:

• Spring Awakening – Moritz (Yugoslav Drama Theatre)
• Rušenje naroda u dva dela – Obrad (Yugoslav Drama Theatre)
• In Search of Marcel Proust – Duke (Yugoslav Drama Theatre)
• Nijinsky – Nijinsky (Yugoslav Drama Theatre)
• Blue Bird – multiple roles (Yugoslav Drama Theatre)
• Salome – Salome (Yugoslav Drama Theatre)
• Hamlet – Hamlet (National Theatre Belgrade)
• Macbeth – Macbeth (MTM)
• Frida Kahlo – Diego Rivera (Madlenianum)
• The Shore, the Dump – Jason (Swan Theatre)
• Wolfman – Horvat (National Theatre Kikinda)
  …among many others in both classical and contemporary repertoire.

His film and television work includes notable roles in:

• Prokleta Avlija – Young Man in White Shirt
• Već viđeno – Young Stole
• Kuća pored pruge – Mitar
• Metla bez drške – Vladimir
• Jastuk groba mog – Pavle Solarić
• Milena iz Praga – Franz Kafka
• Harold and Mod – Harold
• Srpski film – Marko

In addition to performing, he has a distinguished pedagogical career, teaching acting and stage movement at institutions including the Faculty of Dramatic Arts in Belgrade, BK Academy, Faculty of Dramatic Arts in Cetinje, and the Academy of Arts in Osijek. He has also participated in numerous international workshops and seminars in theatre, movement, and acting techniques, collaborating with masters such as Eugenio Barba, Josy Oida, and Tanja Zgonc. He has received numerous awards recognizing his excellence in performance and contribution to theatre, including:

• Best Young Actor for Spring Awakening, MESS Festival, Sarajevo (1987)
• Special Award for Theatre Language Research for Nijinsky at the Small Sterija Theatre Festival
• Debut Film Award at the Niš Film Festival for Kuća pored pruge
• European Acting Award “Gordana Kosanović”, Theater an der Ruhr
• Best Actor for Hamlet, Yugoslav Theatre Festival, Užice (2004)
• Best Actor for Horvat, Festival of Classics, Vršac (2006)
• Raša Plaović Award for Best Acting Achievement, Belgrade Theatres (2014/2015)
• Public Recognition for exceptional contribution to the National Theatre in Belgrade (2014/2015)
• Best Male Role, Brčko Festival (2016)
• National Theatre Award for Best Premiere Performance in the 2019/2020 season for Night Writer, text and direction by Jan Fabre
• Golden Medal “Maja Dimitrijević” and Audience Award “Siniša Dašić” at the 46th Festival of Monodrama and Pantomime, Zemun, for Night Writer
• Golden Badge (2021) in recognition of two decades of service at the National Theatre in Belgrade

Currently, he is a permanent member of the Drama Ensemble at the National Theatre, holding the position of Principal Actor, performing a range of roles in the ongoing repertoire.